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See us on the
cover of spectroscopyNOW.com this month... |
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Click Here
To See Our
SMASH2006
Special Offers!
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Coupling Constants
Links to What's New in
Capillary NMR |
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Protasis is committed
to connecting life science researchers to innovative new microtechnologies. |
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December, 2006 © Protasis |
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NMR Front Page News |
Featured Abstract |
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Quick! Go to:
http://www.spectroscopynow.com/
Microcoils boost NMR.
Current capillary NMR technology is reviewed,
including its applications for the characterization of mass-limited,
small-molecule and protein samples and the rapid screening of
small-molecule or protein libraries. Hyphenated techniques are also
covered. [December 5, 2006]
Protasis is pleased to make the cover of spectroscopyNOW.com this month with a nice introduction to Capillary NMR in
a ten-page review
article published recently in Angewandte Chemie Int. Ed.
by Frank Schroeder
and Matthew Gronquist.
Want a reprint of the entire review article?
Click here. We'll send it. |
Extending the Scope
of NMR
Spectroscopy
with
Microcoil Probes
by Frank C. Schroeder, Harvard Medical
School
and Matthew Gronquist, SUNY College at
Fredonai
Capillary NMR spectroscopy
has emerged as a major breakthrough for increasing the mass-sensitivity of
NMR spectroscopic analysis and enabling the combination of NMR spectroscopy
with other analytical techniques. Not only is the acquisition of
high-sensitivity spectra getting easier, but the quality of CapNMR spectra
obtained in many small-molecule applications exceeds what can be
accomplished with conventional designs. This Minireview discusses
current CapNMR technology and its applications for the characterization of
mass-limited, small molecule and protein samples, the rapid screening of
small-molecule and protein samples, the rapid screening of small-molecule or
protein libraries, as well as hyphenated techniques that combine CapNMR with
other analytical techniques. |
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See the related 2005 journal paper by Frank
Schroeder, et al.
And see the 2005 'Firefly' press release in Royal
Soc. Chem.
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Join Our Next e-Seminar
Bringing Nature Back to Drug Discovery,
by Mark O'Neil-Johnson, Sequoia Sciences, St. Louis
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SMASH Wrap-Up
September, 10 - 13th
Burlington, VT
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Please register at:
http://www.protasis.com/seminar/WhatsNew2006/ |
See all the SMASH 2006 Highlights
at the e-Seminar on December 13th!
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Date : December 13, 2006
Time : 3:30 PM EST |
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Protasis Corporation is pleased to present an e-seminar
on Wednesday, Dec. 13th from
3:30 - 5:00PM EDT
via conference call
for anyone interested in
learning about the latest trends in MicroFlow NMR.
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We typically use the
fall SMASH conference to check-in with our customers and learn about new
trends in small molecule NMR and this year was no exception. Tim Peck,
Bob Albrecht and Dave Strand were there with a CTC/LEAP liquid handler
demonstrating the robotics, fluidics and software for our record-setting
One-Minute NMR platforms.
About twenty of our
current customers visited with us over the four days that we were there.
Some of these users are running hundreds of samples per month and
supporting dozens of synthesis chemists to create smooth-running,
trouble-free departmental Open-Access HT-NMR automation systems. We
interviewed these customers and gave them a demo of the latest One-Minute
NMR software. To hear what they told us, request our SMASH 2006
Wrap-Up Letter.
Request Wrap-Up Letter and Info Package
Request Poster
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Sequoia Sciences was founded to deliver to
the drug discovery process a structurally diverse library of natural
products isolated from plants. The proprietary design of this library
allows the screening of these compounds at optimal HTS concentrations
without non-drug-like interferences. In order to facilitate the rapid
identification of potential leads, Sequoia has built an analytical process
that can facilitate the rapid isolation and structure elucidation of active
compounds. Paramount to the success of our structure elucidation efforts,
Sequoia has relied solely on NMR data acquisition using the Protasis’
remarkable CapNMR™
probe. Moreover, we have applied our proprietary chemistry procedures and
innovative technologies in our internal antibacterial program, discovering a
variety of compounds that show promising inhibition of bacterial biofilms
and are synthetically accessible. |
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View Full Announcement
Contact
David Strand at 508-481-4163
or
by
email at
d.strand@protasis
for questions or additional details.
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See Protasis SMASH Special Offers
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One-Minute
NMR: Efficient Microplate NMR
Automation |
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Protasis Web Site |
One-Minute NMR |
MicroFlow NMR |
MicroNMR Technical |
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Natural Products |
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