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  HTSL-1100 High Throughput Sample Loader
 

  The Protasis HTSL-1100TM High Throughput Sample Loader is an interface between the traditional macro world and the emerging world of high performance microfluidic applications. Sample is injected through an injection port adapter on your LEAP PAL Liquid Handler.  Sample size is custom-configured by cutting capillary tubing to the appropriate length for the desired volume. Once filled, the incorporated Micro Injection Valve delivers the sample for processing.  Built-in pressure monitoring provides safe shutdown in the event of overpressure.
  With the arrival of miniaturized instruments and the pressure to screen vast libraries of molecules, effective liquid handling is an essential automation need in drug discovery and development.  The Protasis HTSL-1100 meets researchers growing need for faster, automated analysis of microvolume samples with low disperson.

The High Throughput Sample Loader can be used to load/infuse samples for a nuclear magnetic resonance or mass spectrometer as well as a variety of configurations where one pump and two rotary valves must be automated. Other applications for the device include use as a nutrient or reagent feed for biochemistry research and as microfluidic support for microchemistry device development.

The loader can be controlled via RS-232 or contact closure interfaces and can be used with popular liquid handlers to allow unattended, high-throughput sample loading. Actuation time is less than 150msec and software is included for dynamic process control.

The device’s positive displacement pump delivers sample injections at precise flow rates of 1-20 uL/min. Loading times are from 2-5 minutes, depending on transfer tubing length and ID. The device is pressure rated to 2,000 psi (138 bar), and all wetted surface materials are biocompatible with excellent chemical compatibility.  

 

This Protasis device is an integrated system containing an Scivex Micro Injection Valve, a Scivex Micro Shut-Off Valve and a Scivex Precision Displacement Pump (100uL stainless-steel pumphead).  Both Micro Valves use Upchurch 1/32" Nuts for tubing connections.  Custom configurations are available for instrument manufacturers, including 50 and 250uL pump head options. Please contact us for more information.

 

HTSL-1100-10         High Throughput Sample Loader with Manual Injector Option

HTSL-1100-16         HTSL with Manual Injector Option and LEAP Startup Kit

HTSL-1100-24         HTSL-1100-16 with LEAP HTC PAL Liquid Handler (Complete)