The increased challenges to remain cost-competitive, increased regulatory oversight, and an increased awareness of environmental responsibility have forced all of us to accept new strategies for efficiency in our consumption of raw materials and disposal of waste. One of the unique advantages of the minute amount of sample and solvent required for microflow NMR is the ease of handling the samples and solvents before and after the run. Before the run, only small amounts are required, translating to shorter work-up times, less costly processing, and less space-intensive storage solutions. After the run, the “droplet” (literally) of sample can sometimes be sent to waste, meaning that your hazardous waste bill at the end of the year for capillary-scale operation is about the same as that for a single day with conventional-scale operation. When sample recollection is required, the ability to utilize microvial or microwell plate (user choice) storage formats provides NMR facilities with a range of product and storage options more traditionally utilized by mass spectrometry or optical analytical methods. This can mean a greater compatibility with the other groups in your facility, and facilitates standardization for further boost in efficiency. Microflow brings NMR into compatibility with other analytical approaches, minimizes disposal costs, and maximizes the efficiency of sample analysis.