The consumption of only milliliters of solvent during a continuous 24-hour run at the capillary-scale means that you can afford to spend a little more on the quality of the solvent, and makes possible the exclusive use of costly deuterated solvents for NMR analysis.  Further, the minute requirement of only microliters of sample means that in some cases you may be able to consider the sample disposable.  This can mean elimination of the expense (laboratory technician support, quality control verification) involved with transfer of samples from protonated solvent to (NMR-preferred) deuterated solvent and then back again to protonated solvent for down-stream analyses by subsequent analytical groups.  In cases where the sample is so precious that it cannot be lost, Protasis/MRM offers a return-to-vial or return-to-well option.  Added flexibility at a price that you can afford – the microflow way.