NMR is inherently sensitive to the magnetic environment of the sample, and consequently to the composition of the sample. Hyphenated LC-NMR applications have demonstrated that compositional variations (e.g. solvent gradients) result in time-dependent magnetic field perturbations that can destroy spin coherence. The diffusion-based process of re-stabilization toward equilibrium is greatly enhanced in geometries that possess a large surface-to-volume ratio. By definition, this means that smaller geometries are better suited to rapid restoration of equilibrium conditions than are larger geometries. This means that programmed variations in flow conditions (e.g. solvent gradient LC runs) as well as unintentional variations (solvent/sample mismatches) can both be accommodated more quickly with the CapNMR probe, resulting in shorter wait periods for you to get the data you desire. Less time, less money, and greater sensitivity performance, all in a simple-to-use package, make microflow NMR the technique of choice that many are turning to for addressing their application needs.