Easy shimming

Protasis CapNMR probes employ small-volume NMR flowcells (5 and 10 mL) into which the sample is loaded for NMR analysis.  Not only is less sample required for analysis than is required in larger-volume probes, but an added benefit of the small size scale is that the spatial region over which magnetic field (B0) homogeneity is required (for high spectral resolution) is greatly reduced as well.  This in turn means that the challenges of shimming are significantly reduced over the case of larger volume samples, and consequently, the process of shimming is greatly simplified.  In general, CapNMR probes shim in a matter of minutes using a small fraction (< 7, typical) channels of the total available shim system.  Shimming between samples is typically not required – in fact, once shimmed, the probe typically does not require re-shimming except for solvent change or when re-installing the probe after removal from the magnet.  This translates to easier usage, less time adjusting, and more time for taking data.